An interview with David McClay.

Novel Negative Regulator of the Wnt Pathway

RacGap50C is a Novel Negative Regulator of the Wnt Pathway by Whitney McRae Jones University Program in Genetics and Genomics Duke University Date:_______________________ Approved: ___________________________ Amy Bejsovec, Supervisor ___________________________ John Klingensmith, Committee Chair ___________________________ David McClay ___________________________ Tannishtha Reya _______________...

INTERCELLULAR SIGNALING PATHWAYS IN THE INITIATION OF MAMMALIAN FOREBRAIN DEVELOPMENT by

INTERCELLULAR SIGNALING PATHWAYS IN THE INITIATION OF MAMMALIAN FOREBRAIN DEVELOPMENT by Yu-Ping Yang Program in Genetics Duke University Date: March 16, 2007 . Approved: ___________________________ John Klingensmith, Supervisor ___________________________ Blanche Capel ___________________________ Margaret L. Kirby ___________________________ Elwood Linney ___________________________ David R. M...

2. Archenteron Morphogenesis in the Sea Urchin

Developmental gene regulatory networks in sea urchins and what we can learn from them [version 1; referees: 3 approved]

Sea urchin embryos begin zygotic transcription shortly after the egg is fertilized. Throughout the cleavage stages a series of transcription factors are activated and, along with signaling through a number of pathways, at least 15 different cell types are specified by the beginning of gastrulation. Experimentally, perturbation of contributing transcription factors, signals and receptors and the...

Correction: Comparative Developmental Transcriptomics Reveals Rewiring of a Highly Conserved Gene Regulatory Network during a Major Life History Switch in the Sea Urchin Genus Heliocidaris

[This corrects the article DOI: 10.1371/journal.pbio.1002391.].